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Immobilized enzyme is also called the solid-phase enzyme,with the development of enzyme engineering in 1960s, which is a newtechnology of enzyme application. It is to bind or restrict soluble enzyme tosolid material by physical or chemical methods ,so that it becomes insoluble but still has itsexclusive enzyme activity, which is used for various enzyme catalytic reactionsin solution.
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Compared with the free enzyme, the immobilized enzyme has the advantagesof high stability, easy separation and recovery, reusable use, and easyproduction continuity and automation. Up to now, immobilized enzyme technologyhas been widely used in food, medicine, agriculture, environmental protection,textile, photography, energy, materials, fine chemical industry, detection andanalysis and other fields, greatly expanding the industrial application ofenzymes, with great potential and broad development prospects.
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There are many kinds of solid materials that can be used as carriers forimmobilization of enzymes, the common ones are natural polymer materials,synthetic polymer materials, porous inorganic materials, etc. Enzyme immobilizationhas high requirements on the particle size, pore structure, binding site andform, mechanical strength, thermal stability, chemical stability, biologicalaffinity and compatibility of the carrier material, and there are differencesamong different enzymes. The structure and properties of the carrier materialdirectly determine the performance of the immobilized enzyme.
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Zhejiang Zhengguang has a relatively complete range of immobilized enzyme carriers with a variety of skeletons, pore structures and binding groups.
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